Biochemical Study on the Role of Curcumin in Male Rabbits

Abstract

Districts. We have therefore investigate the effects of either 15 mg/kg B.W. doses of curcumin on the levels of biochemical parameters in male New Zealand White rabbits. Animals were orally given 15 mg/kg B.W. doses of curcumin. The tried measurements were given to rabbits each other day for 6 weeks.. Treatment with curcumin caused significant (P < 0:05) decrease in the concentrations of glucose, plasma asparatate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) activities, gamma glutamyl transferase activity (ɣ-GT), Plasma thiobarbituric acid-reactive substances (TBARS) and bilirubin. Contrariwise, the total protein (TP)was significantly increased in plasma. Concentrations of urea. But, creatinine, cholesterol, triglycerides (TG), low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) were significantly decreased, while high density lipoprotein (HDL) was increased. The aim of this study was to evaluate the potential of increasing levels of turmeric powder as phytogenic additives on serum biochemical metabolites and antioxidant enzyme activities in growing rabbits.