Satagetegic Approaches for Colon Targeted Drug Delivery System an Overview of Recent Advancement

Manisha P. More, Nikita K. Gaydhane, Dhanshree S. Doras, Ravindra L. Bakal


The colon is a domain in which each nearby and systemic shipping of pills can take place. Local shipping permits topical remedy of inflammatory bowel disease. However, remedy may be made powerful if the medication may be centered without delay into the colon, thereby decreasing the systemic aspect effects. This review, particularly compares the number one techniques for CDDS (Colon Specific Drug Delivery) particularly prodrugs, pH and time structured systems, and microbially caused systems, which completed restricted fulfillment and had obstacles in comparison with more modern CDDS particularly pressure managed colonic shipping capsules, CODESTM, and osmotic managed drug shipping which might be specific in phrases of accomplishing in vivo web website online specificity, and feasibility of producing process


Colon; Noninvasive Drug Delivery; Inflammatory Bowel Diseases; Colorectal Cancer; Protein Drugs

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